The best antiaging treatment depends on your specific concerns and skin condition. For overall effectiveness, daily sunscreen use is the number one preventive treatment. Prescription tretinoin (retinoic acid) is considered the gold standard for wrinkles and skin texture. For immediate wrinkle reduction, Botox relaxes muscles causing expression lines. Dermal fillers restore lost volume in cheeks and lips. Laser resurfacing and intense pulsed light (IPL) treat sun damage and stimulate collagen. Chemical peels improve texture and tone. Microneedling with radiofrequency tightens skin. The most effective approach combines professional treatments with a consistent at-home routine using proven ingredients and sun protection.